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Polynucleotides treat under-eye dark circles and hollows by regenerating thin, crepey skin rather than filling it. Most patients need 2 to 3 sessions, two to three weeks apart, with results building over 8 to 12 weeks. They suit people whose dark circles come from skin quality, not deep volume loss.
Dark circles and hollowing under the eyes are consistently among the top three concerns patients bring to our Wimpole Street clinic. They make you look tired, older, and unwell, even when you feel perfectly fine.
Most under-eye concerns are not caused by what is happening on the surface of the skin. They are caused by what is happening beneath it. This is why polynucleotide injections have become one of the most effective solutions available.
Why under-eye dark circles are so difficult to treat
The skin beneath the eyes is the thinnest skin on the body, 0.5mm vs 2mm on the cheeks. As we age, this thin skin loses collagen and elastin, becoming even thinner and more translucent.
Volume loss in the tear trough compounds the problem by creating shadows that deepen the appearance of dark circles.
This combination of thinning skin, translucency, reduced collagen, and volume loss is what makes under-eye dark circles so resistant to topical treatments. At our clinic at 2 Wimpole Street, in the heart of the Harley Street medical district, this is the starting point of every under-eye assessment.
How polynucleotides address the root cause
Polynucleotides work at a cellular level. When injected into the delicate under-eye skin, they stimulate fibroblast activity, activating the cells responsible for producing collagen and elastin.
Over the following weeks, the skin thickens, strengthens, and regenerates. Blood flow improves. Dark circles soften, crepey texture smooths.
Unlike dermal fillers, which can look unnatural in this delicate area, polynucleotides work with your skin’s own biology. If you have seen this treatment advertised under another name, our explainer on the salmon DNA skin treatment covers where the DNA fragments actually come from. See our skin boosters guide for hydration-focused alternatives.
What to expect from treatment
The treatment takes approximately 30 minutes. Topical anaesthetic for comfort. Slight swelling or minor bruising for 24 to 48 hours. No significant downtime.
Most patients require 2 to 3 sessions spaced 2 to 3 weeks apart. Improvements develop over weeks. Visible improvement within 3 to 4 weeks.
Under-eye polynucleotide pricing
From £300 per syringe per session.
→ Explore polynucleotides at DimAllure
→ Book your consultation
DimAllure
2nd Floor, 2 Wimpole St, London W1G 0EB
Personally administered by Dima Alomar, GPhC-registered Clinical Prescriber Pharmacist
Book your consultation →
Related reading: polynucleotides, Profhilo and skin boosters compared.
Your £50 consultation fee is fully redeemable against your treatment.
