Polynucleotide Injections for Under-Eye Dark Circles and Hollows

Polynucleotide Injections for Under-Eye Dark Circles and Hollows

Polynucleotide injections under-eye dark circles treatment London
Dima Alomar
GPhC-Registered Clinical Prescriber
Written by Dima AlomarGPhC Registered PrescriberMedically AccurateUpdated April 2026

Dark circles and hollowing under the eyes are consistently among the top three concerns patients bring to our Wimpole Street clinic. They make you look tired, older, and unwell, even when you feel perfectly fine.

Most under-eye concerns are not caused by what is happening on the surface of the skin. They are caused by what is happening beneath it. This is why polynucleotide injections have become one of the most effective solutions available.

Why under-eye dark circles are so difficult to treat

The skin beneath the eyes is the thinnest skin on the body, 0.5mm vs 2mm on the cheeks. As we age, this thin skin loses collagen and elastin, becoming even thinner and more translucent.

Volume loss in the tear trough compounds the problem by creating shadows that deepen the appearance of dark circles.

This combination of thinning skin, translucency, reduced collagen, and volume loss is what makes under-eye dark circles so resistant to topical treatments.

How polynucleotides address the root cause

Polynucleotides work at a cellular level. When injected into the delicate under-eye skin, they stimulate fibroblast activity, activating the cells responsible for producing collagen and elastin.

Over the following weeks, the skin thickens, strengthens, and regenerates. Blood flow improves. Dark circles soften, crepey texture smooths.

Unlike dermal fillers, which can look unnatural in this delicate area, polynucleotides work with your skin's own biology. See our skin boosters guide for hydration-focused alternatives.

What to expect from treatment

The treatment takes approximately 30 minutes. Topical anaesthetic for comfort. Slight swelling or minor bruising for 24–48 hours. No significant downtime.

Most patients require 2–4 sessions spaced 2–3 weeks apart. Improvements develop over weeks. Visible improvement within 3–4 weeks.

Under-eye polynucleotide pricing

From £250 per syringe per session. 10% discount on subsequent sessions when booked together.

→ Explore polynucleotides at DimAllure
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DimAllure
2 Wimpole Street, Marylebone, London
Personally administered by Dima Alomar, GPhC-registered Clinical Prescriber Pharmacist
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Not sure which is right for you?

Book a consultation at DimAllure and Dima will assess your facial anatomy personally and recommend the right treatment for your goals.

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Can You Have Both?

Absolutely — and many patients at DimAllure do. Sculptra and fillers are highly complementary. A common approach is to use Sculptra to restore structural collagen across the temples, cheeks, and jawline, then use a small amount of filler for precise, targeted enhancement in areas like the lips or tear troughs.

Summary

  • Timing: Fillers are immediate. Sculptra is gradual.
  • Longevity: Sculptra lasts longer (up to 24 months).
  • Reversibility: Fillers can be dissolved. Sculptra cannot.
  • Mechanism: Fillers add volume. Sculptra rebuilds collagen.
  • Best use: Fillers for specific areas. Sculptra for structural support.

At DimAllure, consultations are £50 and fully redeemable against your treatment — so there is no financial pressure and no obligation to proceed on the day.

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Ready to Discuss Your Treatment Options?

Book a consultation at 2 Wimpole Street, Marylebone. Dima will assess your anatomy and recommend the right treatment for your goals. £50, fully redeemable.

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